where condition based on not null column

Question

 

I have table like Table1 and columns like Col1,col2,col3,col4,col5...upto col15

my pocedure valirable is @NP1 

now i want to check if col1is null or empty then check for col2... like upto col15

like select *from  table where Col1= @NP1

dont want to use isnull or case