EDPLUS for Excel to datatable

Question

 var pck = new OfficeOpenXml.ExcelPackage(); 

pck.Load(File.OpenRead("~\\EXCELS\\Book2.xlsx"));

How to map excel after hosting ... 

I tried this code it is not working for me.

I tried system path it works but after hosting doesn't work

it shows

Could not find a part of the path 'C:\Windows\SysWOW64\inetsrv\~\EXCELS\Book2.xlsx'.

Can anyone help me please..