We have used ajax call with "async: false" through out our web application, now in Safari browser(in Windows and Mac OS both) if response gets delayed more than 5 seconds Safari browser throws dom timeout exeption.
$.ajax({
type: "POST",
contentType: "application/json; charset=utf-8",
url: "Web method url",
data: jsonData,
async: false,
success: function (data) {
},
error: function (data) {
},
complete: function () {
}
});