ASP.NET 3.5: There is no direct method to access data from client side. We can go for any of these methods

1) Pagemethods of script manager
2) ICallbackEventHandler interface
3) XMLHttphanlder component

ASP.NET 4.0: In this framework there is an inbuilt feature for this. Following are the methods to implement them.

1) Client data controls
2) Client templates
3) Client data context