Objective:
In this article, I am going to show how we could work with SharePoint items using object model or in other words using .Net code. I will show you 
- How to add item into the SharePoint list? 
 - How to retrieve item from the SharePoint list? 
 - How to update item into the SharePoint list? 
 - How to delete item from the SharePoint list?
 
Assumption: 
- I have created a custom list called Reader. 
 - There are two columns. One is Reader'sName. This is a single line text column. Second is Reader'sArticle. This is numeric column. 
 - I have put some item also in Reader list. 
 
In SharePoint site, Reader list look like as below, 

Here, I assume you know how to create a custom list in a SharePoint site and how to put some data into that. If you do not know, read my article on the same here on this site. Now I am going to manipulate the above list through code. 
I am going to follow the below steps. 
- Create a window application 
 - Add reference of Microsoft.SharePoint dll. 
 - Add few controls like buttons and text boxes. I am a bad UI designer. So don't follow my window form here. You design of yours. 
 - Return a site collection using SPSite. 
 - Return particular website where list is added using SPWeb. 
 - Return collection of list items using SPListItemCollection. 
 - Work with a particular list item using SPListItem.
 
Adding Microsoft.SharePoint dll

Design of the Form 
- There are two text boxes. 
 - Three buttons to add, delete and update.
 
 
Explanation 
- I am returning the site collection on the form load. 
 - I am returning the top level site also on form load.
 
Adding to the List 
- Readers is name of the list 
 - I am returning the List collection and adding the item into that. 
 - I am reading the items to be added from the textboxes. 
 
private void btnAdd_Click(object sender, EventArgs e)
{
        string Name = txtName.Text;
        int Numofarticle = Convert.ToInt32(txtNumberofArticle.Text); 
        _ItemCollection = _MyWeb.Lists["Readers"].Items  ;
        _MyItem = _ItemCollection.Add();
        _MyItem["Reader'sName"] = Name;
        _MyItem["Reader'sArticle"] = Numofarticle;
        _MyItem.Update();
        txtName.Text = "";
        txtNumberofArticle.Text = "";
        MessageBox.Show("Item Added");
}
Updating to the List 
- 
Readers is name of the list 
 - 
I am returning the List collection and updating the item into that. 
 - 
I am reading the items to be added from the textboxes. 
 - 
I am iterating through the collection and searching for the Reader'sName to be updated.
 
private void btnEdit_Click(object sender, EventArgs e)
{
        _ItemCollection = _MyWeb.Lists["Readers"].Items;
        int count = _ItemCollection.Count;
        for (int i = 0; i < count; i++)
        {
            SPListItem item = _ItemCollection[i];
            if (item["Reader'sName"].ToString() == txtName.Text.ToString())
            {
                item["Reader'sArticle"] = Convert.ToInt32(txtNumberofArticle.Text);
                item.Update();
            }
        }
        MessageBox.Show("Updated");
    }
}
Deleting from the List 
- 
Readers is name of the list 
 - 
I am returning the List collection and updating the item into that. 
 - 
I am reading the items to be added from the textboxes. 
 - 
I am iterating through the collection and searching for the Reader'sName to be deleted
 
private void btnDelete_Click(object sender, EventArgs e)
{
    _ItemCollection = _MyWeb.Lists["Readers"].Items;
    int count = _ItemCollection.Count;
    for (int i = 0; i < count; i++)
    {
        SPListItem item = _ItemCollection[i];
        if (item["Reader'sName"].ToString() == txtName.Text.ToString())
        {
            _ItemCollection.Delete(i);
            count--;
        }
    }
    MessageBox.Show("Deleted");
}
For reference the whole code is as below, 
using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Linq;
using System.Text;
using System.Windows.Forms;
using Microsoft.SharePoint;  
namespace ProgrammingList
{
    public partial class Form1 : Form
    {
        SPSite _MySite = null;
        SPWeb _MyWeb = null;
        SPListItemCollection _ItemCollection = null;
        SPListItem _MyItem = null;       
        public Form1()
        {
            InitializeComponent();
        }
        private void btnAdd_Click(object sender, EventArgs e)
        {
            MessageBox.Show(_MyWeb.Title);
            string Name = txtName.Text;
            int Numofarticle = Convert.ToInt32(txtNumberofArticle.Text); 
            _ItemCollection = _MyWeb.Lists["Readers"].Items  ;
            _MyItem = _ItemCollection.Add();
            _MyItem["Reader'sName"] = Name;
            _MyItem["Reader'sArticle"] = Numofarticle;
            _MyItem.Update();
            txtName.Text = "";
            txtNumberofArticle.Text = "";
            MessageBox.Show("Item Added");
        }
        private void Form1_Load(object sender, EventArgs e)
        {
            _MySite = new SPSite("http://adfsaccount:2222/");
           // _MyWeb = _MySite.AllWebs["Document Center"];
            _MyWeb =_MySite.OpenWeb(); 
        }
        private void btnDelete_Click(object sender, EventArgs e)
        {
            _ItemCollection = _MyWeb.Lists["Readers"].Items;
            int count = _ItemCollection.Count;
            for (int i = 0; i < count; i++)
            {
                SPListItem item = _ItemCollection[i];
                if (item["Reader'sName"].ToString() == txtName.Text.ToString())
                {
                    _ItemCollection.Delete(i);
                    count--;
                }
            }
            MessageBox.Show("Deleted");     
        }
        private void btnEdit_Click(object sender, EventArgs e)
        {
            _ItemCollection = _MyWeb.Lists["Readers"].Items;
            int count = _ItemCollection.Count;
            for (int i = 0; i < count; i++)
            {
                SPListItem item = _ItemCollection[i];
                if (item["Reader'sName"].ToString() == txtName.Text.ToString())
                {
                    item["Reader'sArticle"] = Convert.ToInt32(txtNumberofArticle.Text);
                    item.Update();
                }
            }
            MessageBox.Show("Updated");
        }
    }
}
Conclusion:
In this article, I showed how to manipulate SharePoint list using code. Thanks for reading. 
Happy Coding