Windows Forms ASP.NET Web Application User Interfaces data binding etc. Easy to build Difficult to build Deployment and Maintenance Complex. New versions of assemblies configuration files and other required files must be deployed on all client machines. Usually user interaction required. Easy. Need to deploy assemblies and configuration files on the server only. Transparent to the client. Performance Faster Slower Robustness and Reliability One client machine goes down other users are still live. Usually web servers are never down. However if the server goes down all users are affected. Network Congestion Depending on the data transfer and connections made to the server from various clients. Depends Resources Runs on the client machine. Runs on a Web server. Catastrophic failure User interaction required. Usually user interaction not required. Framework dependency All client machines have to install required versions of .NET framework and other required libraries. Only server needs to have .NET framework and other required libraries. http://www.c-sharpcorner.com/Blogs/416/