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I need more details,would you please make some changes on sample which has been sent to you?
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Do in Document.ready function of Jquery.
1. Bind main dropdownlist and provide ID of dropdownlist selected from Model.
2. then if first dropdownlist is selected then call your ajax script Document.ready function in to bind Second dropdownlist and then to set selected values just get value from Model and set it.
Reference :-
http://www.c-sharpcorner.com/UploadFile/4d9083/filter-webgrid-with-cascading-dropdownlist-along-with-paging/